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CG15812 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38379, updated on 9-Dec-2024

Summary

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Official Symbol
CG15812provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035405
Locus tag
Dmel_CG15812
See related
AllianceGenome:FB:FBgn0035405
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15812; pfk; Pfk
Summary
Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central brain anlage; central brain primordium; ganglia; gonad; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG15812 in Genome Data Viewer
Location:
63B7-63B8; 3-6 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3159991..3162019)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3159991..3162019)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene BTB-protein-VII Neighboring gene NADH dehydrogenase (ubiquinone) 30 kDa subunit Neighboring gene rasp Neighboring gene ASCIZ zinc finger protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The bric à brac locus consists of two paralogous genes encoding BTB/POZ domain proteins and acts as a homeotic and morphogenetic regulator of imaginal development in Drosophila. Couderc JL, et al. Development, 2002 May. PMID 11973274
  2. Sightless has homology to transmembrane acyltransferases and is required to generate active Hedgehog protein. Lee JD, et al. Curr Biol, 2001 Jul 24. PMID 11509241
  3. Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodeling and Xbp1. Martínez Corrales G, et al. Nat Aging, 2022 Dec. PMID 37118537, Free PMC Article
  4. Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Chamoun Z, et al. Science, 2001 Sep 14. PMID 11486055
  5. Widespread evidence of cooperative DNA binding by transcription factors in Drosophila development. Kazemian M, et al. Nucleic Acids Res, 2013 Sep. PMID 23847101, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15812-PA
CG15812-PB
piefke

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3159991..3162019
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079173.5 → NP_523897.2  uncharacterized protein Dmel_CG15812, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523897.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MYX0, Q9VZU3
    Related
    FBpp0072891
    Conserved Domains (3) summary
    smart00225
    Location:35 → 118
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:20 → 113
    BTB; BTB/POZ domain
    pfam05225
    Location:458 → 501
    HTH_psq; helix-turn-helix, Psq domain

  2. NM_167991.2 → NP_728817.1  uncharacterized protein Dmel_CG15812, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728817.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86BP7, Q8MYX0
    Related
    FBpp0072892
    Conserved Domains (3) summary
    smart00225
    Location:29 → 112
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:14 → 107
    BTB; BTB/POZ domain
    pfam05225
    Location:452 → 495
    HTH_psq; helix-turn-helix, Psq domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86BP7 Q86BP7
Q8MYX0 Q8MYX0
Q9VZU3 Q9VZU3

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