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CG1271 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38364, updated on 4-Jan-2025

Summary

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Official Symbol
CG1271provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035392
Locus tag
Dmel_CG1271
See related
AllianceGenome:FB:FBgn0035392
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1271
Summary
Predicted to be involved in glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Predicted to be active in mitochondrion. Is expressed in adult head. Orthologous to human GK5 (glycerol kinase 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG1271 in Genome Data Viewer
Location:
63A5-63A5; 3-5 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3052514..3054906)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3052514..3054906)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Sphingosine kinase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conserved family of glycerol kinase loci in Drosophila melanogaster. Martinez Agosto JA, et al. Mol Genet Metab, 2006 Aug. PMID 16545593, Free PMC Article
  2. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
  3. Gliogenesis in Drosophila: genome-wide analysis of downstream genes of glial cells missing in the embryonic nervous system. Egger B, et al. Development, 2002 Jul. PMID 12091301
  4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
  5. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
NOT enables glycerol kinase activity IKR
Inferred from Key Residues
more info
 PubMed 
NOT enables transferase activity IKR
Inferred from Key Residues
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycerol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycerol-3-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in triglyceride metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1271-PA
CG1271-PB
CG1271-PC
CG1271-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3052514..3054906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206259.2 → NP_995981.1  uncharacterized protein Dmel_CG1271, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995981.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KV84
    Conserved Domains (2) summary
    COG0554
    Location:50 → 315
    GlpK; Glycerol kinase [Energy production and conversion]
    cl17037
    Location:1 → 345
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  2. NM_167974.2 → NP_728796.1  uncharacterized protein Dmel_CG1271, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728796.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I939
    Related
    FBpp0072856
    Conserved Domains (2) summary
    COG0554
    Location:50 → 405
    GlpK; Glycerol kinase [Energy production and conversion]
    cl17037
    Location:1 → 402
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

  3. NM_139506.3 → NP_647763.1  uncharacterized protein Dmel_CG1271, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647763.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YTX2, Q95S17, Q9VZV9
    Related
    FBpp0072857
    Conserved Domains (2) summary
    cd07793
    Location:32 → 552
    FGGY_GK5_metazoa; metazoan glycerol kinase 5-like proteins; belongs to the FGGY family of carbohydrate kinases
    COG0554
    Location:32 → 555
    GlpK; Glycerol kinase [Energy production and conversion]

  4. NM_167973.2 → NP_728795.1  uncharacterized protein Dmel_CG1271, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728795.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YTX2, Q8I940
    Related
    FBpp0072858
    Conserved Domains (2) summary
    cd07793
    Location:32 → 535
    FGGY_GK5_metazoa; metazoan glycerol kinase 5-like proteins; belongs to the FGGY family of carbohydrate kinases
    COG0554
    Location:32 → 538
    GlpK; Glycerol kinase [Energy production and conversion]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KV84 Q7KV84
Q7YTX2 Q7YTX2
Q8I939 Q8I939
Q8I940 Q8I940
Q8IGI3 Q8IGI3
Q9VZV9 Q9VZV9

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