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mRpS35 mitochondrial ribosomal protein S35 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38345, updated on 4-Jan-2025

Summary

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Official Symbol
mRpS35provided by FlyBase
Official Full Name
mitochondrial ribosomal protein S35provided by FlyBase
Primary source
FLYBASE:FBgn0035374
Locus tag
Dmel_CG2101
See related
AllianceGenome:FB:FBgn0035374
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2101; Dmel\CG2101; MRP-S28
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial small ribosomal subunit. Is expressed in adult head and adult heart. Orthologous to human MRPS35 (mitochondrial ribosomal protein S35). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See mRpS35 in Genome Data Viewer
Location:
62F4-62F4; 3-4 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (2780899..2782105)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (2780899..2782105)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Autophagy-related 2 Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 6 Neighboring gene Ten-Eleven Translocation (TET) family protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article
  2. The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. Cavdar Koc E, et al. J Biol Chem, 2001 Jun 1. PMID 11279123
  3. C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A. Moens TG, et al. Acta Neuropathol, 2019 Mar. PMID 30604225, Free PMC Article
  4. C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Lee KH, et al. Cell, 2016 Oct 20. PMID 27768896, Free PMC Article
  5. The ribosomal protein genes and Minute loci of Drosophila melanogaster. Marygold SJ, et al. Genome Biol, 2007. PMID 17927810, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial translation TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial small ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
mitochondrial ribosomal protein S35
Names
CG2101-PA
mRpS35-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    2780899..2782105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079169.3 → NP_523893.1  mitochondrial ribosomal protein S35 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523893.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZX6
    Related
    FBpp0290840
    Conserved Domains (1) summary
    pfam10213
    Location:160 → 281
    MRP-S28; Mitochondrial ribosomal subunit protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZX6 Q9VZX6

Gene LinkOut

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