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Cpr62Bc Cuticular protein 62Bc [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38241, updated on 9-Dec-2024

Summary

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Official Symbol
Cpr62Bcprovided by FlyBase
Official Full Name
Cuticular protein 62Bcprovided by FlyBase
Primary source
FLYBASE:FBgn0035281
Locus tag
Dmel_CG1919
See related
AllianceGenome:FB:FBgn0035281
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1919; DmelCpr62Bc; Dmel\CG1919
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. Is expressed in several structures, including adult head; embryonic epipharynx; embryonic head epidermis; epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Cpr62Bc in Genome Data Viewer
Location:
62B7-62B7; 3-1.0 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1840281..1842084, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1840281..1842084, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 62Ba Neighboring gene Cuticular protein 62Bb Neighboring gene CNMamide Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extensive gene amplification and concerted evolution within the CPR family of cuticular proteins in mosquitoes. Cornman RS, et al. Insect Biochem Mol Biol, 2008 Jun. PMID 18510978, Free PMC Article
  2. High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae. Wang M, et al. Dev Cell, 2022 May 23. PMID 35512700
  3. [Identification of C(2)M interacting proteins by yeast two-hybrid screening]. Yue SS, et al. Yi Chuan, 2015 Nov. PMID 26582530
  4. Elucidating the "Gravome": Quantitative Proteomic Profiling of the Response to Chronic Hypergravity in Drosophila. Hosamani R, et al. J Proteome Res, 2016 Dec 2. PMID 27648494
  5. Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. Yatsenko AS, et al. BMC Med, 2020 Jan 21. PMID 31959160, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cuticular protein 62Bc
Names
CG1919-PA
CG1919-PB
Cpr62Bc-PA
Cpr62Bc-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    1840281..1842084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139411.2 → NP_647668.1  cuticular protein 62Bc, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647668.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W077
    Related
    FBpp0072748
    Conserved Domains (1) summary
    pfam00379
    Location:54 → 106
    Chitin_bind_4; Insect cuticle protein

  2. NM_001274364.1 → NP_001261293.1  cuticular protein 62Bc, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261293.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W077
    Conserved Domains (1) summary
    pfam00379
    Location:54 → 106
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W077 Q9W077

Gene LinkOut

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