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Zkscan7 zinc finger with KRAB and SCAN domains 7 [ Mus musculus (house mouse) ]

Gene ID: 382118, updated on 27-Nov-2024

Summary

Official Symbol
Zkscan7provided by MGI
Official Full Name
zinc finger with KRAB and SCAN domains 7provided by MGI
Primary source
MGI:MGI:3040678
See related
Ensembl:ENSMUSG00000063488 AllianceGenome:MGI:3040678
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp167
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZKSCAN7 (zinc finger with KRAB and SCAN domains 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E11.5 (RPKM 2.2), CNS E14 (RPKM 1.6) and 25 other tissues See more
Orthologs
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Genomic context

See Zkscan7 in Genome Data Viewer
Location:
9 F4; 9 73.21 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (122715883..122727684)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (122886818..122898619)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6814 Neighboring gene T cell activation inhibitor, mitochondrial Neighboring gene predicted gene, 35549 Neighboring gene zinc finger protein 445 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:122775118-122775301 Neighboring gene zinc finger protein 660 Neighboring gene zinc finger protein 105

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General protein information

Preferred Names
zinc finger protein with KRAB and SCAN domains 7
Names
zinc finger protein 167

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177505.2NP_001170976.1  zinc finger protein with KRAB and SCAN domains 7

    See identical proteins and their annotated locations for NP_001170976.1

    Status: VALIDATED

    Source sequence(s)
    AC125374
    Consensus CDS
    CCDS52970.1
    UniProtKB/TrEMBL
    E9PVW1
    Related
    ENSMUSP00000071695.6, ENSMUST00000063980.8
    Conserved Domains (6) summary
    smart00431
    Location:46156
    SCAN; leucine rich region
    COG5048
    Location:333702
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:601621
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:487509
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:46133
    SCAN; SCAN domain
    pfam13465
    Location:501526
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    122715883..122727684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155097.1XP_036010990.1  zinc finger protein with KRAB and SCAN domains 7 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:1373
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:269289
    ZF_C2H2; C2H2 Zn finger [structural motif]