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Bgb - Big brother

Enables transcription coactivator activity. Involved in regulation of hemocyte proliferation. Located in nucleus. Is expressed in several structures, including central brain primordium; eye disc posterior to the morphogenetic furrow; eye photoreceptor cell; ganglia; and presumptive embryonic/larval central nervous system. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Orthologous to human CBFB (core-binding factor subunit beta). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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Species Gene Architecture aa