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Ccdc24 coiled-coil domain containing 24 [ Mus musculus (house mouse) ]

Gene ID: 381546, updated on 27-Nov-2024

Summary

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Official Symbol
Ccdc24provided by MGI
Official Full Name
coiled-coil domain containing 24provided by MGI
Primary source
MGI:MGI:2685874
See related
Ensembl:ENSMUSG00000078588 AllianceGenome:MGI:2685874
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1028
Summary
Acts upstream of or within blastocyst hatching. Is expressed in early conceptus. Orthologous to human CCDC24 (coiled-coil domain containing 24). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 58.6), lung adult (RPKM 21.4) and 14 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc24 in Genome Data Viewer
Location:
4 D1; 4 53.69 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (117725946..117729808, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (117869255..117872661, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40232 Neighboring gene peptidylprolyl isomerase A pseudogene 4_1138.1 Neighboring gene solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Neighboring gene UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 Neighboring gene predicted gene, 40233 Neighboring gene predicted gene 12841 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Cui W, et al. Sci Rep, 2016 Nov 21. PMID 27869233, Free PMC Article
  2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within blastocyst hatching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034876.1 → NP_001030048.1  coiled-coil domain-containing protein 24

    See identical proteins and their annotated locations for NP_001030048.1

    Status: VALIDATED

    Source sequence(s)
    AK133118, BG088507, CD774819
    Consensus CDS
    CCDS51281.1
    UniProtKB/TrEMBL
    E9PUW8, Q3V0I8
    Related
    ENSMUSP00000102030.3, ENSMUST00000106422.9
    Conserved Domains (1) summary
    pfam15669
    Location:1 → 173
    CCDC24; Coiled-coil domain-containing protein 24 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    117725946..117729808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503208.3 → XP_006503271.1  coiled-coil domain-containing protein 24 isoform X1

    Conserved Domains (1) summary
    pfam15669
    Location:1 → 116
    CCDC24; Coiled-coil domain-containing protein 24 family

  2. XM_006503209.2 → XP_006503272.1  coiled-coil domain-containing protein 24 isoform X2

    See identical proteins and their annotated locations for XP_006503272.1

    Conserved Domains (1) summary
    pfam15669
    Location:14 → 80
    CCDC24; Coiled-coil domain-containing protein 24 family

  3. XM_030253636.2 → XP_030109496.1  coiled-coil domain-containing protein 24 isoform X3

    UniProtKB/TrEMBL
    E9PUW8
    Related
    ENSMUSP00000129502.2, ENSMUST00000171052.8
    Conserved Domains (1) summary
    pfam15669
    Location:24 → 220
    CCDC24; Coiled-coil domain-containing protein 24 family
Nucleotide Protein Strain
Heading Accession and Version

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