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dpr20 defective proboscis extension response 20 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38101, updated on 9-Dec-2024

Summary

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Official Symbol
dpr20provided by FlyBase
Official Full Name
defective proboscis extension response 20provided by FlyBase
Primary source
FLYBASE:FBgn0035170
Locus tag
Dmel_CG12191
See related
AllianceGenome:FB:FBgn0035170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12191; CT9818; Dmel\CG12191; Dpr-20; Dpr20
Summary
Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. Is expressed in several structures, including antennal primordium; central brain primordium; ganglia; head epidermis primordium; and larval nervous system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See dpr20 in Genome Data Viewer
Location:
61D2-61D2; 3-0.5 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (852720..857248, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (852720..857248, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Centrosomal protein 290kDa Neighboring gene Dodecenoyl-CoA delta-isomerase Neighboring gene uncharacterized protein Neighboring gene Ubiquitin specific protease 10 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons. Bornstein B, et al. EMBO J, 2021 Jun 15. PMID 33847376, Free PMC Article
  2. Molecular evolution and population genetic analysis of candidate female reproductive genes in Drosophila. Panhuis TM, et al. Genetics, 2006 Aug. PMID 16783023, Free PMC Article
  3. Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. Barish S, et al. PLoS Genet, 2018 Aug. PMID 30102700, Free PMC Article
  4. The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila. Rollmann SM, et al. Genetics, 2007 Jun. PMID 17435226, Free PMC Article
  5. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synapse organization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in neuron projection membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
defective proboscis extension response 20
Names
CG12191-PA
dpr20-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    852720..857248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138222.3 → NP_612066.1  defective proboscis extension response 20 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612066.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0L9
    Related
    FBpp0072491
    Conserved Domains (2) summary
    smart00410
    Location:278 → 365
    IG_like; Immunoglobulin like
    cl11960
    Location:279 → 378
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W0L9 Q9W0L9

Gene LinkOut

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