JMJD5 Jumonji domain containing 5 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: JMJD5provided by FlyBase
Official Full Name: Jumonji domain containing 5provided by FlyBase
Primary source: FLYBASE:FBgn0035166
Locus tag: Dmel_CG13902
See related: AllianceGenome:FB:FBgn0035166
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13902; Dmel\CG13902; Kdm8
Summary: Predicted to enable chromatin binding activity; histone H3K36 demethylase activity; and peptidyl-arginine 3-dioxygenase activity. Predicted to be involved in G2/M transition of mitotic cell cycle and negative regulation of DNA-templated transcription. Located in cytoplasm. Orthologous to human KDM8 (lysine demethylase 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (839980..841360, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (839980..841360, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	ISS Inferred from Sequence or Structural Similarity more info
enables histone H3K36 demethylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone H3K36 demethylase activity	ISS Inferred from Sequence or Structural Similarity more info
enables peptidyl-arginine 3-dioxygenase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G2/M transition of mitotic cell cycle	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

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