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Vti1a Vesicle transport through interaction with t-SNAREs 1a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38085, updated on 9-Dec-2024

Summary

Official Symbol
Vti1aprovided by FlyBase
Official Full Name
Vesicle transport through interaction with t-SNAREs 1aprovided by FlyBase
Primary source
FLYBASE:FBgn0260862
Locus tag
Dmel_CG3279
See related
AllianceGenome:FB:FBgn0260862
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3279; Dmel\CG3279; Vti1; VTI1; vti1a; Vti1A
Summary
Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in Golgi vesicle transport; macroautophagy; and retrograde transport, endosome to Golgi. Predicted to be located in Golgi membrane and clathrin-coated vesicle. Predicted to be part of SNARE complex. Predicted to be active in Golgi apparatus; cytoplasmic vesicle membrane; and endoplasmic reticulum membrane. Is expressed in adult head and organism. Orthologous to human VTI1A (vesicle transport through interaction with t-SNAREs 1A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Vti1a in Genome Data Viewer
Location:
61C8-61C8; 3-0.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (691486..692919, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (691486..692919, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene highroad Neighboring gene uncharacterized protein Neighboring gene RabX6 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44514

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables SNAP receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Golgi to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in retrograde transport, endosome to Golgi ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle fusion ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle fusion with Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle fusion with Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
is_active_in ER to Golgi transport vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SNARE complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in clathrin-coated vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vesicle transport through interaction with t-SNAREs 1a
Names
CG3279-PA
VTI1 ortholog
Vti1a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    691486..692919 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138209.4NP_612053.1  vesicle transport through interaction with t-SNAREs 1a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612053.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0N6
    Related
    FBpp0072503
    Conserved Domains (2) summary
    cd15891
    Location:128189
    SNARE_Vti1a; SNARE motif of Vti1b-like
    pfam05008
    Location:1189
    V-SNARE; Vesicle transport v-SNARE protein N-terminus