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RabX6 RabX6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38084, updated on 4-Jan-2025

Summary

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Official Symbol
RabX6provided by FlyBase
Official Full Name
RabX6provided by FlyBase
Primary source
FLYBASE:FBgn0035155
Locus tag
Dmel_CG12015
See related
AllianceGenome:FB:FBgn0035155
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12015; Dmel\CG12015; DmRabX6; rabx6; rabX6
Summary
Predicted to enable GTPase activity. Predicted to be involved in several processes, including Rab protein signal transduction; autophagosome assembly; and intracellular protein transport. Located in neuronal cell body. Is expressed in several structures, including Bolwig organ; adult ensheathing glial cell; brain; imaginal disc; and synaptic neuropil domain. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See RabX6 in Genome Data Viewer
Location:
61C8-61C8; 3-0.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (690517..691951)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (690517..691951)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene highroad Neighboring gene uncharacterized protein Neighboring gene Vesicle transport through interaction with t-SNAREs 1a Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44514

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-resolution in situ hybridization analysis on the chromosomal interval 61C7-61C8 of Drosophila melanogaster reveals interbands as open chromatin domains. Zielke T, et al. Chromosoma, 2016 Jun. PMID 26520107
  2. The bantam gene regulates Drosophila growth. Hipfner DR, et al. Genetics, 2002 Aug. PMID 12196398, Free PMC Article
  3. A new genetic locus controlling growth and proliferation in Drosophila melanogaster. Raisin S, et al. Genetics, 2003 Jul. PMID 12871911, Free PMC Article
  4. Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands. Ma CJ, et al. Commun Integr Biol, 2021 Feb 9. PMID 33628358, Free PMC Article
  5. Multiple Requirements for Rab GTPases in the Development of Drosophila Tracheal Dorsal Branches and Terminal Cells. Best BT, et al. G3 (Bethesda), 2020 Mar 5. PMID 31980432, Free PMC Article

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in Rab protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vesicle ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
RabX6
Names
CG12015-PA
CG12015-PB
RabX6-PA
RabX6-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    690517..691951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138208.4 → NP_612052.1  RabX6, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_612052.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W0N7
    Related
    FBpp0072476
    Conserved Domains (1) summary
    cd00154
    Location:10 → 172
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)

  2. NM_001274290.1 → NP_001261219.1  RabX6, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261219.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PE35
    Conserved Domains (2) summary
    smart00175
    Location:10 → 176
    RAB; Rab subfamily of small GTPases
    cd00154
    Location:10 → 172
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PE35 M9PE35
Q9W0N7 Q9W0N7

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