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Ccdc177 coiled-coil domain containing 177 [ Mus musculus (house mouse) ]

Gene ID: 380768, updated on 27-Nov-2024

Summary

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Official Symbol
Ccdc177provided by MGI
Official Full Name
coiled-coil domain containing 177provided by MGI
Primary source
MGI:MGI:2686414
See related
Ensembl:ENSMUSG00000062961 AllianceGenome:MGI:2686414
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1568
Summary
Orthologous to human CCDC177 (coiled-coil domain containing 177). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in whole brain E14.5 (RPKM 4.6), CNS E14 (RPKM 3.8) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc177 in Genome Data Viewer
Location:
12 C3; 12 37.02 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (80802221..80807489, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (80755447..80760715, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing, family D (with coiled-coil domains) member 1, opposite strand Neighboring gene pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 Neighboring gene predicted gene, 51986 Neighboring gene STARR-seq mESC enhancer starr_32646 Neighboring gene STARR-seq mESC enhancer starr_32647 Neighboring gene STARR-seq mESC enhancer starr_32648 Neighboring gene sushi domain containing 6 Neighboring gene STARR-seq mESC enhancer starr_32649 Neighboring gene STARR-positive B cell enhancer ABC_E5337 Neighboring gene STARR-seq mESC enhancer starr_32653 Neighboring gene STARR-seq mESC enhancer starr_32654 Neighboring gene predicted gene, 23298

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant. Quinlan MA, et al. Front Mol Neurosci, 2020. PMID 32581705, Free PMC Article
  2. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
  3. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
  4. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC91363

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 177

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008423.2 → NP_001008423.2  coiled-coil domain-containing protein 177

    See identical proteins and their annotated locations for NP_001008423.2

    Status: VALIDATED

    Source sequence(s)
    AK147473, BC067044, BY727768
    Consensus CDS
    CCDS26015.1
    UniProtKB/Swiss-Prot
    Q3UHB8, Q6NXJ5
    Related
    ENSMUSP00000072982.7, ENSMUST00000073251.8
    Conserved Domains (1) summary
    pfam15558
    Location:332 → 705
    DUF4659; Domain of unknown function (DUF4659)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    80802221..80807489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UHB8.1 GenPept UniProtKB/Swiss-Prot:Q3UHB8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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