trh - trachealess
Enables DNA-binding transcription factor activity; protein heterodimerization activity; and sequence-specific DNA binding activity. Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including epithelial tube morphogenesis; open tracheal system development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; epithelial tube; ganglia; organism subdivision; and tracheal primordium. Orthologous to human NPAS1 (neuronal PAS domain protein 1) and NPAS3 (neuronal PAS domain protein 3). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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