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CG30427 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37986, updated on 4-Jan-2025

Summary

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Official Symbol
CG30427provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0043792
Locus tag
Dmel_CG30427
See related
AllianceGenome:FB:FBgn0043792
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD36843; CG18680; CG2858; Dmel\CG30427
Summary
Predicted to enable alcohol-forming long-chain fatty acyl-CoA reductase activity and alcohol-forming very long-chain fatty acyl-CoA reductase activity. Involved in determination of adult lifespan. Predicted to be active in peroxisome. Is expressed in several structures, including adult head; antennal primordium; gut section; head epidermis primordium; and somatic precursor cell. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG30427 in Genome Data Viewer
Location:
60E5-60E5; 2-107 cM
Exon count:
16
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24928747..24937477, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20816270..20825000, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Na channel protein 60E Neighboring gene Ribosomal protein L41 Neighboring gene painless Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Troponin C-akin-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of exon-intron structure and alternative splicing in fruit flies and malarial mosquito genomes. Malko DB, et al. Genome Res, 2006 Apr. PMID 16520458, Free PMC Article
  2. Mining gene expression data for pollutants (dioxin, toluene, formaldehyde) and low dose of gamma-irradiation. Moskalev A, et al. PLoS One, 2014. PMID 24475070, Free PMC Article
  3. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article
  4. Gene expression and morphogenesis during the deposition of Drosophila wing cuticle. Adler PN. Fly (Austin), 2017 Jul 3. PMID 28631994, Free PMC Article
  5. Effective but costly, evolved mechanisms of defense against a virulent opportunistic pathogen in Drosophila melanogaster. Ye YH, et al. PLoS Pathog, 2009 Apr. PMID 19381251, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alcohol-forming long-chain fatty acyl-CoA reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in long-chain fatty-acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30427-PA
CG30427-PB
CG30427-PC
CG30427-PD
CG30427-PE
CG30427-PF
CG30427-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24928747..24937477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166697.3 → NP_726498.1  uncharacterized protein Dmel_CG30427, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726498.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D9PTW2, Q8MMC6
    Related
    FBpp0072319
    Conserved Domains (2) summary
    cd05236
    Location:15 → 321
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    pfam03015
    Location:364 → 453
    Sterile; Male sterility protein

  2. NM_001169827.2 → NP_001163298.1  uncharacterized protein Dmel_CG30427, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163298.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BI89, Q960T0, Q9W0Y5
    Conserved Domains (2) summary
    cd05236
    Location:15 → 330
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    pfam03015
    Location:363 → 454
    Sterile; Male sterility protein

  3. NM_001259583.1 → NP_001246512.1  uncharacterized protein Dmel_CG30427, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246512.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D9PTW2, Q8MMC6
    Conserved Domains (2) summary
    cd05236
    Location:15 → 321
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    pfam03015
    Location:364 → 453
    Sterile; Male sterility protein

  4. NM_138136.4 → NP_611980.1  uncharacterized protein Dmel_CG30427, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611980.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BI89, Q960T0, Q9W0Y5
    Related
    FBpp0072320
    Conserved Domains (2) summary
    cd05236
    Location:15 → 330
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    pfam03015
    Location:363 → 454
    Sterile; Male sterility protein

  5. NM_001169828.1 → NP_001163299.1  uncharacterized protein Dmel_CG30427, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163299.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BI89, Q960T0, Q9W0Y5
    Conserved Domains (2) summary
    cd05236
    Location:15 → 330
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    pfam03015
    Location:363 → 454
    Sterile; Male sterility protein

  6. NM_166698.3 → NP_726499.1  uncharacterized protein Dmel_CG30427, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726499.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8W1
    Related
    FBpp0072321
    Conserved Domains (3) summary
    cd05236
    Location:15 → 329
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    COG0451
    Location:15 → 341
    WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
    pfam03015
    Location:363 → 454
    Sterile; Male sterility protein

  7. NM_166699.1 → NP_726500.1  uncharacterized protein Dmel_CG30427, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726500.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8W1
    Related
    FBpp0072322, FBtr0072416
    Conserved Domains (3) summary
    cd05236
    Location:15 → 329
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    COG0451
    Location:15 → 341
    WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
    pfam03015
    Location:363 → 454
    Sterile; Male sterility protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0E8W1 Q0E8W1
Q5BI89 Q5BI89
Q8MMC6 Q8MMC6
Q9W0Y5 Q9W0Y5

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