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CG11414 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37923, updated on 4-Jan-2025

Summary

Official Symbol
CG11414provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035024
Locus tag
Dmel_CG11414
See related
AllianceGenome:FB:FBgn0035024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11414; znf598; ZNF598
Summary
Predicted to enable several functions, including ribosome binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Involved in mitotic cell cycle. Is expressed in adult head. Orthologous to human ZNF598 (zinc finger protein 598, E3 ubiquitin ligase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG11414 in Genome Data Viewer
Location:
60D5-60D5; 2-107 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24561607..24565058)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20449130..20452581)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ion transport peptide Neighboring gene Nucleosome remodeling factor - 38kD Neighboring gene unconventional prefoldin RPB5 interactor Neighboring gene TFIIF-interacting CTD phosphatase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables ribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables zinc ion binding ISM
Inferred from Sequence Model
more info
PubMed 
Process Evidence Code Pubs
involved_in mitotic cell cycle HMP PubMed 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in rescue of stalled ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in rescue of stalled ribosome IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG11414-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24561607..24565058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138088.4NP_611932.2  uncharacterized protein Dmel_CG11414 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611932.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IGT4, Q9W149
    Related
    FBpp0072214
    Conserved Domains (3) summary
    COG5236
    Location:2294
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    pfam13821
    Location:220259
    DUF4187; Domain of unknown function (DUF4187)
    pfam13920
    Location:4494
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)