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CG3494 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37903, updated on 4-Jan-2025

Summary

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Official Symbol
CG3494provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035008
Locus tag
Dmel_CG3494
See related
AllianceGenome:FB:FBgn0035008
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CT11751; Dmel\CG3494
Summary
Predicted to be involved in intracellular signal transduction. Orthologous to human LRRC30 (leucine rich repeat containing 30). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG3494 in Genome Data Viewer
Location:
60D1-60D1; 2-107 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24474299..24475261)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20361822..20362784)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome. Mikhaylova LM, et al. BMC Biol, 2011 May 4. PMID 21542906, Free PMC Article
  2. The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy. Pogson JH, et al. PLoS Genet, 2014 Nov. PMID 25412178, Free PMC Article
  3. Seizure suppression through manipulating splicing of a voltage-gated sodium channel. Lin WH, et al. Brain, 2015 Apr. PMID 25681415, Free PMC Article
  4. CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. Wu M, et al. Sci Rep, 2020 Apr 30. PMID 32355295, Free PMC Article
  5. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3494-PA
CG3494-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24474299..24475261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138071.2 → NP_611915.1  uncharacterized protein Dmel_CG3494, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611915.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8W8
    Related
    FBpp0072202
    Conserved Domains (3) summary
    COG4886
    Location:34 → 231
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:63 → 86
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:85 → 124
    LRR_4; Leucine Rich repeats (2 copies)

  2. NM_166673.2 → NP_726449.1  uncharacterized protein Dmel_CG3494, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726449.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E8W8
    Related
    FBpp0072203
    Conserved Domains (3) summary
    COG4886
    Location:34 → 231
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:63 → 86
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:85 → 124
    LRR_4; Leucine Rich repeats (2 copies)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0E8W8 Q0E8W8

Gene LinkOut

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