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CG43775 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37863, updated on 9-Dec-2024

Summary

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Official Symbol
CG43775provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0264297
Locus tag
Dmel_CG43775
See related
AllianceGenome:FB:FBgn0264297
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13569; CG13569-1; Dmel\CG43775
Summary
Involved in response to virus. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human CRISPLD1 (cysteine rich secretory protein LCCL domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG43775 in Genome Data Viewer
Location:
60B11-60B11; 2-106 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24123167..24126630, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20010690..20014153, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene tamo Neighboring gene Zinc finger protein RP-8 Neighboring gene N(alpha)-acetyltransferase 35

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Insulin-mediated endothelin signaling is antiviral during West Nile virus infection. Trammell CE, et al. J Virol, 2023 Oct 31. PMID 37796127, Free PMC Article
  2. Characterization of the SCP/TAPS gene family in Drosophila melanogaster. Kovalick GE, et al. Insect Biochem Mol Biol, 2005 Aug. PMID 15944079
  3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  4. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
  5. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in multicellular organismal reproductive process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to virus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG43775-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24123167..24126630 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166663.1 → NP_726425.3  uncharacterized protein Dmel_CG43775 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726425.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IRK1, Q8T923
    Related
    FBtr0331500
    Conserved Domains (1) summary
    cd05380
    Location:66 → 228
    SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IRK1 Q8IRK1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials