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CG3860 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37825, updated on 4-Jan-2025

Summary

Official Symbol
CG3860provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034951
Locus tag
Dmel_CG3860
See related
AllianceGenome:FB:FBgn0034951
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3860
Summary
Predicted to enable sterol binding activity. Predicted to be active in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including adult head; ganglia; gastric caecum; gonad; and gut section. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67. Orthologous to several human genes including OSBPL2 (oxysterol binding protein like 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG3860 in Genome Data Viewer
Location:
60B1-60B1; 2-106 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23992138..23995055, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19879661..19882578, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Peptidylglycine-alpha-hydroxylating monooxygenase Neighboring gene PAS kinase Neighboring gene mir-1009 stem loop Neighboring gene Obscurin Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables sterol binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in perinuclear endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG3860-PA
CG3860-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23992138..23995055 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138021.3NP_611865.1  uncharacterized protein Dmel_CG3860, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611865.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1D9
    Related
    FBpp0072110
    Conserved Domains (1) summary
    pfam01237
    Location:26439
    Oxysterol_BP; Oxysterol-binding protein
  2. NM_001299873.1NP_001286802.1  uncharacterized protein Dmel_CG3860, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286802.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LGH8
    Conserved Domains (1) summary
    pfam01237
    Location:26441
    Oxysterol_BP; Oxysterol-binding protein