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Upf3 - Upf3

Predicted to enable mRNA binding activity. Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be active in cytoplasm and nucleolus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Orthologous to human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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Species Gene Architecture aa