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CG5539 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37766, updated on 9-Dec-2024

Summary

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Official Symbol
CG5539provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034907
Locus tag
Dmel_CG5539
See related
AllianceGenome:FB:FBgn0034907
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5539
Summary
Predicted to enable microtubule binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Is expressed in adult head. Orthologous to human REEP4 (receptor accessory protein 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG5539 in Genome Data Viewer
Location:
60A1-60A2; 2-105 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23804811..23806144)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19692334..19693667)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene sol narae Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Structure specific recognition protein Neighboring gene uncharacterized protein Neighboring gene NTF2-related export protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins. Yalçın B, et al. Elife, 2017 Jul 25. PMID 28742022, Free PMC Article
  2. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
  3. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
  4. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum tubular network organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum tubular network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5539-PA
CG5539-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23804811..23806144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299853.1 → NP_001286782.1  uncharacterized protein Dmel_CG5539, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286782.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3S2, Q9W1J5
    Conserved Domains (1) summary
    pfam03134
    Location:8 → 94
    TB2_DP1_HVA22; TB2/DP1, HVA22 family

  2. NM_137987.2 → NP_611831.2  uncharacterized protein Dmel_CG5539, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611831.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T3S2, Q9W1J5
    Related
    FBpp0072032, FBtr0072123
    Conserved Domains (1) summary
    pfam03134
    Location:8 → 94
    TB2_DP1_HVA22; TB2/DP1, HVA22 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T3S2 Q8T3S2
Q9W1J5 Q9W1J5

Gene LinkOut

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