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CG33934 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772159, updated on 9-Dec-2024

Summary

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Official Symbol
CG33934provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0064119
Locus tag
Dmel_CG33934
See related
AllianceGenome:FB:FBgn0064119
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.217; CG32921; CG32921-ORFB; CG4961; Dmel\CG33934
Summary
Predicted to enable citrate transmembrane transporter activity and succinate transmembrane transporter activity. Predicted to be involved in citrate transport; succinate transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Orthologous to several human genes including SLC13A2 (solute carrier family 13 member 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG33934 in Genome Data Viewer
Location:
92C3-92C4; 3-67 cM
Exon count:
25
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20042757..20048716)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15868479..15874438)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene trade embargo Neighboring gene Regnase 1 Neighboring gene identity crisis Neighboring gene uncharacterized protein Neighboring gene I'm not dead yet 2 Neighboring gene uncharacterized protein Neighboring gene midlife crisis Neighboring gene Rhodopsin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular evolution under increasing transposable element burden in Drosophila: a speed limit on the evolutionary arms race. Castillo DM, et al. BMC Evol Biol, 2011 Sep 14. PMID 21917173, Free PMC Article
  2. Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction. François CM, et al. Nat Commun, 2023 Oct 23. PMID 37872135, Free PMC Article
  3. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
  4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables citrate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables succinate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in citrate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in succinate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG33934-PC
CG33934-PD
CG33934-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20042757..20048716
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170189.1 → NP_001163660.1  uncharacterized protein Dmel_CG33934, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163660.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIQ7
    Conserved Domains (2) summary
    TIGR00785
    Location:45 → 540
    dass; anion transporter
    cl21473
    Location:52 → 524
    ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...

  2. NM_001032028.2 → NP_001027199.2  uncharacterized protein Dmel_CG33934, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027199.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KI47
    Conserved Domains (2) summary
    TIGR00785
    Location:45 → 539
    dass; anion transporter
    cl21473
    Location:52 → 523
    ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...

  3. NM_001032029.2 → NP_001027200.2  uncharacterized protein Dmel_CG33934, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027200.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KI47
    Conserved Domains (2) summary
    TIGR00785
    Location:45 → 539
    dass; anion transporter
    cl21473
    Location:52 → 523
    ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JIQ7 E1JIQ7
Q0KI47 Q0KI47

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