U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Gr64e Gustatory receptor 64e [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3771916, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Gr64eprovided by FlyBase
Official Full Name
Gustatory receptor 64eprovided by FlyBase
Primary source
FLYBASE:FBgn0045476
Locus tag
Dmel_CG32258
See related
AllianceGenome:FB:FBgn0045476
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14988; CG32258; CG33157; Dmel64e; Dmel\CG32258; DmGr64e; Gr64; Gr64A2; gr64e; GR64e
Summary
Enables ionotropic sweet taste receptor activity. Involved in sensory perception of sweet taste. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult PNS neuron; adult cervical connective; adult labellum sensillum; subesophageal nerve; and tarsal segment. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Gr64e in Genome Data Viewer
Location:
64A4-64A4; 3-10 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4032141..4035703)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4032141..4035703)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 64a Neighboring gene Gustatory receptor 64c Neighboring gene Gustatory receptor 64b Neighboring gene Gustatory receptor 64d Neighboring gene antisense RNA:CR45042 Neighboring gene Gustatory receptor 64f Neighboring gene uncharacterized protein Neighboring gene Reduction in Cnn dots 5

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional dissociation in sweet taste receptor neurons between and within taste organs of Drosophila. Thoma V, et al. Nat Commun, 2016 Feb 19. PMID 26893070, Free PMC Article
  2. Smells like evolution: the role of chemoreceptor evolution in behavioral change. Cande J, et al. Curr Opin Neurobiol, 2013 Feb. PMID 22884223
  3. Deciphering the Genes for Taste Receptors for Fructose in Drosophila. Uchizono S, et al. Mol Cells, 2017 Oct. PMID 29047261, Free PMC Article
  4. Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. Jiao Y, et al. Curr Biol, 2008 Nov 25. PMID 19026541, Free PMC Article
  5. Drosophila HCN mediates gustatory homeostasis by preserving sensillar transepithelial potential in sweet environments. Lee M, et al. Elife, 2024 Jul 29. PMID 39073076, Free PMC Article

See all (71) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ionotropic sweet taste receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables ligand-gated monoatomic ion channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables sweet taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables taste receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in sensory perception of sweet taste IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of sweet taste IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sensory perception of sweet taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
gustatory receptor 64e
Names
CG32258-PA
CG32258-PB
Gr64e-PA
Gr64e-PB
gustatory receptor 64A2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4032141..4035703
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168051.3 → NP_728923.2  gustatory receptor 64e, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728923.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P83296, Q8IRC5, Q9VZJ5
    Conserved Domains (1) summary
    pfam06151
    Location:49 → 449
    Trehalose_recp; Trehalose receptor

  2. NM_001031935.2 → NP_001027106.1  gustatory receptor 64e, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027106.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7KV53
    Conserved Domains (1) summary
    pfam06151
    Location:58 → 458
    Trehalose_recp; Trehalose receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P83296.2 P83296
Q7KV53 Q7KV53

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools