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CG13531 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37627, updated on 4-Jan-2025

Summary

Official Symbol
CG13531provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034786
Locus tag
Dmel_CG13531
See related
AllianceGenome:FB:FBgn0034786
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG13531
Summary
Predicted to be involved in several processes, including axo-dendritic transport; axon extension; and synaptic vesicle transport. Predicted to be active in several cellular components, including axon; dendrite; and synapse. Is expressed in adult head. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See CG13531 in Genome Data Viewer
Location:
59B2-59B3; 2-101 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22847832..22853827, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18735355..18741350, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L23 Neighboring gene inactivation no afterpotential D Neighboring gene forkhead domain 59A

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in axo-dendritic transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in axon extension ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in synaptic vesicle transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in axon ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG13531-PB
CG13531-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22847832..22853827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299819.1NP_001286748.1  uncharacterized protein Dmel_CG13531, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286748.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1Y8
    Conserved Domains (1) summary
    pfam14649
    Location:14521746
    Spatacsin_C; Spatacsin C-terminus
  2. NM_137882.2NP_611726.1  uncharacterized protein Dmel_CG13531, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611726.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W1Y8
    Related
    FBpp0071821
    Conserved Domains (1) summary
    pfam14649
    Location:14521746
    Spatacsin_C; Spatacsin C-terminus