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Obp59a Odorant-binding protein 59a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37605, updated on 4-Jan-2025

Summary

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Official Symbol
Obp59aprovided by FlyBase
Official Full Name
Odorant-binding protein 59aprovided by FlyBase
Primary source
FLYBASE:FBgn0034766
Locus tag
Dmel_CG13517
See related
AllianceGenome:FB:FBgn0034766
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
59a; CG13517; DmelObp59a; Dmel\CG13517; Obp58a; OBP59a
Summary
Predicted to enable odorant binding activity. Involved in response to low humidity. Predicted to be located in extracellular region. Is expressed in antennal segment 3 sense organ and hygrosensitive sensory organ. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Obp59a in Genome Data Viewer
Location:
59A3-59A3; 2-101 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22702695..22703786)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18590200..18591291)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44764 Neighboring gene roundabout 1 Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 58b Neighboring gene Odorant-binding protein 58c

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Humidity response depends on the small soluble protein Obp59a in Drosophila. Sun JS, et al. Elife, 2018 Sep 19. PMID 30230472, Free PMC Article
  2. Molecular mechanisms of olfactory detection in insects: beyond receptors. Schmidt HR, et al. Open Biol, 2020 Oct. PMID 33022193, Free PMC Article
  3. Modulation of feeding behavior by odorant-binding proteins in Drosophila melanogaster. Swarup S, et al. Chem Senses, 2014 Feb. PMID 24302688, Free PMC Article
  4. Functional dissection of Odorant binding protein genes in Drosophila melanogaster. Swarup S, et al. Genes Brain Behav, 2011 Aug. PMID 21605338, Free PMC Article
  5. Organization and function of Drosophila odorant binding proteins. Larter NK, et al. Elife, 2016 Nov 15. PMID 27845621, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in response to low humidity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Odorant-binding protein 59a
Names
CG13517-PB
Obp59a-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22702695..22703786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176249.3 → NP_788429.1  Odorant-binding protein 59a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788429.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q29QE9, Q86BF9
    Related
    FBpp0071781
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86BF9.1 Q86BF9

Gene LinkOut

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