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CG30280 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37522, updated on 9-Dec-2024

Summary

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Official Symbol
CG30280provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050280
Locus tag
Dmel_CG30280
See related
AllianceGenome:FB:FBgn0050280
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AAF46801; CG6676; Dmel\CG30280; FBpp0071673
Summary
Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to several human genes including FIBCD1 (fibrinogen C domain containing 1) and MFAP4 (microfibril associated protein 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG30280 in Genome Data Viewer
Location:
58B8-58B9; 2-98 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22113589..22114841)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18001094..18002346)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene flapper Neighboring gene Pleckstrin homology and RUN domain containing M1 Neighboring gene Verprolin 1 Neighboring gene uncharacterized protein Neighboring gene meiotic from via Salaria 332

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of the fibrinogen-like domain of fibrinogen-related proteins in the mosquito, Anopheles gambiae, and the fruitfly, Drosophila melanogaster, genomes. Wang X, et al. BMC Genomics, 2005 Sep 8. PMID 16150145, Free PMC Article
  2. Evolution and potential function of fibrinogen-like domains across twelve Drosophila species. Middha S, et al. BMC Genomics, 2008 May 30. PMID 18513432, Free PMC Article
  3. FlyXCDB-A Resource for Drosophila Cell Surface and Secreted Proteins and Their Extracellular Domains. Pei J, et al. J Mol Biol, 2018 Sep 14. PMID 29890119
  4. Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Zdobnov EM, et al. Science, 2002 Oct 4. PMID 12364792
  5. Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila. Walls S, et al. Cell Rep, 2020 Dec 8. PMID 33242407, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in collagen-containing extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30280-PD
Fibrinogen-related protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    22113589..22114841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137797.5 → NP_611641.6  uncharacterized protein Dmel_CG30280 [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    E2RTZ8, Q4V4U2, Q9W291
    Conserved Domains (1) summary
    cd00087
    Location:65 → 279
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V4U2 Q4V4U2

Gene LinkOut

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