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Plekhm1 - Pleckstrin homology and RUN domain containing M1

Enables small GTPase binding activity. Involved in secretory granule-lysosome fusion. Is expressed in organism. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 6 and osteopetrosis. Orthologous to several human genes including PLEKHM1 (pleckstrin homology and RUN domain containing M1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa