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ppk9 pickpocket 9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37498, updated on 9-Dec-2024

Summary

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Official Symbol
ppk9provided by FlyBase
Official Full Name
pickpocket 9provided by FlyBase
Primary source
FLYBASE:FBgn0085398
Locus tag
Dmel_CG34369
See related
AllianceGenome:FB:FBgn0085398
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13489; CG13490; CG34369; Dmel\CG34369
Old locus tag
CG13489; CG13490; Dmel_CG13489; Dmel_CG13490
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See ppk9 in Genome Data Viewer
Location:
58A4-58A4; 2-97 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21964173..21970664)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17851678..17858169)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Ben-Shahar Y. Adv Genet, 2011. PMID 22099690, Free PMC Article
  2. Evolution of the Insect PPK Gene Family. Latorre-Estivalis JM, et al. Genome Biol Evol, 2021 Sep 1. PMID 34390578, Free PMC Article
  3. The genetic architecture of degenerin/epithelial sodium channels in Drosophila. Zelle KM, et al. G3 (Bethesda), 2013 Mar. PMID 23449991, Free PMC Article
  4. SCORE: a computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data. Site clustering over random expectation. Rebeiz M, et al. Proc Natl Acad Sci U S A, 2002 Jul 23. PMID 12107285, Free PMC Article
  5. Molecular and cellular basis of sodium sensing in Drosophila labellum. Asefa WR, et al. iScience, 2024 Jul 19. PMID 39015148, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables sodium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pickpocket 9
Names
CG34369-PA
CG34369-PB
ppk9-PA
ppk9-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21964173..21970664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299771.1 → NP_001286700.1  pickpocket 9, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286700.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LG42
    Conserved Domains (1) summary
    pfam00858
    Location:154 → 579
    ASC; Amiloride-sensitive sodium channel

  2. NM_137778.2 → NP_611622.2  pickpocket 9, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611622.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2B5
    Conserved Domains (1) summary
    pfam00858
    Location:154 → 587
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LG42 A0A0B4LG42
Q9W2B5 Q9W2B5

Gene LinkOut

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