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PpN58A Protein phosphatase N at 58A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37493, updated on 9-Dec-2024

Summary

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Official Symbol
PpN58Aprovided by FlyBase
Official Full Name
Protein phosphatase N at 58Aprovided by FlyBase
Primary source
FLYBASE:FBgn0025573
Locus tag
Dmel_CG3245
See related
AllianceGenome:FB:FBgn0025573
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3245; Dmel\CG3245; DmPpN-58A; PPN; PPN 58A; PpN-58A
Summary
Predicted to enable protein serine/threonine phosphatase activity. Located in nucleus. Is expressed in testis. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See PpN58A in Genome Data Viewer
Location:
58A3-58A3; 2-97 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21881352..21882533, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17768857..17770038, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene cookie monster Neighboring gene Fish-lips Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning of a novel testis specific protein serine/threonine phosphatase, PPN 58A, from Drosophila melanogaster. Armstrong CG, et al. Biochim Biophys Acta, 1998 Aug 20. PMID 9765603
  2. Genomic analysis of Drosophila chromosome underreplication reveals a link between replication control and transcriptional territories. Belyakin SN, et al. Proc Natl Acad Sci U S A, 2005 Jun 7. PMID 15928082, Free PMC Article
  3. Transcriptional activation in Drosophila spermatogenesis involves the mutually dependent function of aly and a novel meiotic arrest gene cookie monster. Jiang J, et al. Development, 2003 Feb. PMID 12490562
  4. Evolution of gene sequence in response to chromosomal location. Díaz-Castillo C, et al. Genetics, 2007 Sep. PMID 17890366, Free PMC Article
  5. Protein phosphatase 4--from obscurity to vital functions. Cohen PT, et al. FEBS Lett, 2005 Jun 13. PMID 15913612

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase N at 58A
Names
CG3245-PA
PpN58A-PA
NP_477384.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21881352..21882533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058036.4 → NP_477384.1  protein phosphatase N at 58A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477384.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O77294, Q7KVM5, Q8SXA5
    Related
    FBpp0071650, FBtr0071734
    Conserved Domains (2) summary
    PTZ00480
    Location:22 → 311
    PTZ00480; serine/threonine-protein phosphatase; Provisional
    cl13995
    Location:23 → 311
    MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77294 O77294
Q7KVM5 Q7KVM5
Q8SXA5 Q8SXA5

Gene LinkOut

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