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Ip6k Inositol hexakisphosphate kinase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37465, updated on 9-Dec-2024

Summary

Official Symbol
Ip6kprovided by FlyBase
Official Full Name
Inositol hexakisphosphate kinaseprovided by FlyBase
Primary source
FLYBASE:FBgn0034644
Locus tag
Dmel_CG10082
See related
AllianceGenome:FB:FBgn0034644
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0172774.149; CG10082; Dmel\CG10082; dmIP6K
Summary
Predicted to enable inositol hexakisphosphate kinase activity. Predicted to be involved in inositol phosphate biosynthetic process and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including amnioserosa; ganglia; glial cell; gut section; and hypodermal muscle cell of A1-7. Orthologous to human IP6K1 (inositol hexakisphosphate kinase 1); IP6K2 (inositol hexakisphosphate kinase 2); and IP6K3 (inositol hexakisphosphate kinase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Ip6k in Genome Data Viewer
Location:
57F6-57F6; 2-96 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21646177..21657935)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17533682..17545440)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR42547 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43786 Neighboring gene NADH dehydrogenase (ubiquinone) B12 subunit Neighboring gene Rae1 Neighboring gene poor Imd response upon knock-in

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables inositol hexakisphosphate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables inositol hexakisphosphate kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in inositol phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in inositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphatidylinositol phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phosphatidylinositol phosphate biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
inositol hexakisphosphate kinase
Names
3-hydroxyisobutyryl-CoA hydrolase
CG10082-PA
CG10082-PB
Ip6k-PA
Ip6k-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    21646177..21657935
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166466.3NP_726095.2  inositol hexakisphosphate kinase, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726095.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2E9
    Related
    FBpp0071578
    Conserved Domains (2) summary
    pfam03770
    Location:303450
    IPK; Inositol polyphosphate kinase
    cl12283
    Location:821894
    IPK; Inositol polyphosphate kinase
  2. NM_137751.4NP_611595.3  inositol hexakisphosphate kinase, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611595.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IRK4, Q961X0
    Related
    FBpp0071579
    Conserved Domains (2) summary
    pfam03770
    Location:73220
    IPK; Inositol polyphosphate kinase
    cl12283
    Location:591664
    IPK; Inositol polyphosphate kinase