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CG10543 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37379, updated on 4-Jan-2025

Summary

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Official Symbol
CG10543provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034570
Locus tag
Dmel_CG10543
See related
AllianceGenome:FB:FBgn0034570
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10543
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Involved in gravitaxis. Predicted to be active in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG10543 in Genome Data Viewer
Location:
57B5-57B5; 2-92 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20996220..21007740)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16883725..16895245)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene dim gamma-tubulin 3 Neighboring gene Proteasome alpha3 subunit Neighboring gene uncharacterized protein Neighboring gene grauzone

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gravitaxis in Drosophila melanogaster: a forward genetic screen. Armstrong JD, et al. Genes Brain Behav, 2006 Apr. PMID 16594976
  2. Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome. Herranz R, et al. Mol Ecol, 2010 Oct. PMID 20819157
  3. Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland. Tokusumi Y, et al. PLoS One, 2012. PMID 22911822, Free PMC Article
  4. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973
  5. A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development. Schertel C, et al. Genome Res, 2015 Apr. PMID 25568052, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in gravitaxis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10543-PA
CG10543-PD
CG10543-PE
CG10543-PF
CG10543-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20996220..21007740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001274183.1 → NP_001261112.1  uncharacterized protein Dmel_CG10543, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261112.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KFE1
    Conserved Domains (2) summary
    PHA00733
    Location:804 → 860
    PHA00733; hypothetical protein
    sd00017
    Location:868 → 888
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001382009.1 → NP_001369100.1  uncharacterized protein Dmel_CG10543, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3Q7L9
    Conserved Domains (2) summary
    PHA00733
    Location:804 → 860
    PHA00733; hypothetical protein
    sd00017
    Location:868 → 888
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. NM_137690.4 → NP_611534.2  uncharacterized protein Dmel_CG10543, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611534.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MLW9, Q9W2N8
    Related
    FBpp0071453
    Conserved Domains (2) summary
    PHA00733
    Location:804 → 860
    PHA00733; hypothetical protein
    sd00017
    Location:868 → 888
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. NM_166416.2 → NP_726015.2  uncharacterized protein Dmel_CG10543, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726015.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MLW9, Q9W2N8
    Conserved Domains (2) summary
    PHA00733
    Location:804 → 860
    PHA00733; hypothetical protein
    sd00017
    Location:868 → 888
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. NM_176241.3 → NP_788421.2  uncharacterized protein Dmel_CG10543, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788421.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86BG2
    Conserved Domains (2) summary
    PHA00733
    Location:801 → 857
    PHA00733; hypothetical protein
    sd00017
    Location:865 → 885
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KFE1 A0A0B4KFE1
A0A6M3Q7L9 A0A6M3Q7L9
Q86BG2 Q86BG2
Q8MSN5 Q8MSN5
Q9W2N8 Q9W2N8

Gene LinkOut

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