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CG11110 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37337, updated on 4-Jan-2025

Summary

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Official Symbol
CG11110provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034535
Locus tag
Dmel_CG11110
See related
AllianceGenome:FB:FBgn0034535
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11110; Imp
Summary
Predicted to enable endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to be located in membrane. Predicted to be part of mitochondrial inner membrane peptidase complex. Is expressed in adult head. Orthologous to human IMMP2L (inner mitochondrial membrane peptidase subunit 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG11110 in Genome Data Viewer
Location:
57A8-57A8; 2-91 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20641742..20642558)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16529247..16530063)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene rigor mortis Neighboring gene uncharacterized protein Neighboring gene maf-S Neighboring gene RNA polymerase III subunit K Neighboring gene Threonyl-carbamoyl synthesis 1 Neighboring gene DNA methyltransferase 1 associated protein 1 Neighboring gene Leucine-rich tendon-specific protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial processing peptidases. Gakh O, et al. Biochim Biophys Acta, 2002 Sep 2. PMID 12191769
  2. The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F. Bugga L, et al. Mol Cell Biol, 2009 Jun. PMID 19332563, Free PMC Article
  3. An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion. Zhang S, et al. Genes Dev, 2006 Jul 15. PMID 16815999, Free PMC Article
  4. Seizure suppression through manipulating splicing of a voltage-gated sodium channel. Lin WH, et al. Brain, 2015 Apr. PMID 25681415, Free PMC Article
  5. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein processing involved in protein targeting to mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein processing involved in protein targeting to mitochondrion IEA
Inferred from Electronic Annotation
more info
  
involved_in signal peptide processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial inner membrane peptidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial inner membrane peptidase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11110-PA
serine-type peptidase
NP_611501.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20641742..20642558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137657.3 → NP_611501.1  uncharacterized protein Dmel_CG11110 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611501.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QQ12
    Related
    FBpp0085545
    Conserved Domains (2) summary
    cd06530
    Location:27 → 136
    S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...
    TIGR02227
    Location:27 → 142
    sigpep_I_bact; signal peptidase I, bacterial type
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4QQ12 Q4QQ12

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