pip4k2ca phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pip4k2caprovided by ZNC
Official Full Name: phosphatidylinositol-5-phosphate 4-kinase, type II, gamma aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030828-9
See related: Ensembl:ENSDARG00000031020 AllianceGenome:ZFIN:ZDB-GENE-030828-9
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb770; pip5k2; Pip5k2c; pip4k2c; zgc:56046
Summary: Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and 1-phosphatidylinositol-5-phosphate 4-kinase activity. Predicted to be involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process. Predicted to act upstream of or within phosphatidylinositol metabolic process and phosphorylation. Predicted to be located in endoplasmic reticulum. Predicted to be active in plasma membrane. Is expressed in gut; pectoral fin musculature; polster; and pronephric duct. Orthologous to human PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (36616634..36645156)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (36494393..36522695)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb18d10.y1 (e-PCR)
- UniSTS:190246

fk24h05.x1 (e-PCR)
- UniSTS:200694

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 1-phosphatidylinositol-4-phosphate 5-kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables 1-phosphatidylinositol-5-phosphate 4-kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 1-phosphatidylinositol-5-phosphate 4-kinase activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphatidylinositol metabolic process	IEA Inferred from Electronic Annotation more info
involved_in phosphatidylinositol phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

Names: 1-phosphatidylinositol-5-phosphate 4-kinase C; PI(5)P 4-kinase type II gamma; PIP4KII-gamma; phosphatidylinositol 5-phosphate 4-kinase type II gamma; phosphatidylinositol-4-phosphate 5-kinase, type II, gamma

NP_956395.3

EC 2.7.1.149

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200101.3 → NP_956395.3 phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

Status: VALIDATED

Source sequence(s)

BX321896

UniProtKB/Swiss-Prot

Q6IQE1, Q7ZVF5

Related

ENSDARP00000042700.5, ENSDART00000042701.6