U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

tapas tapas [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37304, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
tapasprovided by FlyBase
Official Full Name
tapasprovided by FlyBase
Primary source
FLYBASE:FBgn0027529
Locus tag
Dmel_CG8920
See related
AllianceGenome:FB:FBgn0027529
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD21403; CG8920; Dmel\CG8920; tap; Tapas; TDRD7
Summary
Involved in secondary piRNA processing and transposable element silencing by piRNA-mediated mRNA destabilization. Located in P granule and perinuclear region of cytoplasm. Is expressed in several structures, including adult brain cell body rind; adult optic lobe; egg chamber; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in cataract 36. Orthologous to human TDRD7 (tudor domain containing 7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See tapas in Genome Data Viewer
Location:
56F16-56F16; 2-90 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20319180..20325973)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16206685..16213478)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44642 Neighboring gene uncharacterized protein Neighboring gene Mediator complex subunit 8 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage. Jeske M, et al. Genes Dev, 2017 May 1. PMID 28536148, Free PMC Article
  2. The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster. Patil VS, et al. BMC Biol, 2014 Oct 6. PMID 25287931, Free PMC Article
  3. Silencing of Transposable Elements by piRNAs in Drosophila: An Evolutionary Perspective. Luo S, et al. Genomics Proteomics Bioinformatics, 2017 Jun. PMID 28602845, Free PMC Article
  4. Global identification of bursicon-regulated genes in Drosophila melanogaster. An S, et al. BMC Genomics, 2008 Sep 18. PMID 18801173, Free PMC Article
  5. Conservation of an RNA regulatory map between Drosophila and mammals. Brooks AN, et al. Genome Res, 2011 Feb. PMID 20921232, Free PMC Article

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in secondary piRNA processing IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in secondary piRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transposable element silencing by piRNA-mediated mRNA destabilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in P granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tapas
Names
CG8920-PA
CG8920-PB
CG8920-PD
CG8920-PF
tapas-PA
tapas-PB
tapas-PD
tapas-PF

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20319180..20325973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137631.7 → NP_611475.3  tapas, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611475.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E910
    Conserved Domains (3) summary
    cd04508
    Location:1087 → 1131
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    cd09972
    Location:7 → 92
    LOTUS_TDRD_OSKAR; The first LOTUS domain in Oskar and Tudor-containing proteins 5 and 7
    pfam00567
    Location:1032 → 1151
    TUDOR; Tudor domain

  2. NM_001169742.2 → NP_001163213.1  tapas, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163213.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JGN5, Q6AWL6
    Conserved Domains (2) summary
    cd09972
    Location:7 → 92
    LOTUS_TDRD_OSKAR; The first LOTUS domain in Oskar and Tudor-containing proteins 5 and 7
    pfam00567
    Location:563 → 673
    TUDOR; Tudor domain

  3. NM_137630.4 → NP_611474.1  tapas, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611474.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6AWL6, Q7KN83
    Related
    FBpp0085593
    Conserved Domains (1) summary
    pfam00567
    Location:477 → 587
    TUDOR; Tudor domain

  4. NM_153771.4 → NP_722455.3  tapas, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722455.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    D5AEP3
    Conserved Domains (2) summary
    cd04508
    Location:1001 → 1045
    TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
    pfam00567
    Location:946 → 1065
    TUDOR; Tudor domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D5AEP3 D5AEP3
E1JGN5 E1JGN5
Q0E910 Q0E910
Q7KN83 Q7KN83
Q95SJ5 Q95SJ5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools