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ppk6 pickpocket 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37286, updated on 9-Dec-2024

Summary

Official Symbol
ppk6provided by FlyBase
Official Full Name
pickpocket 6provided by FlyBase
Primary source
FLYBASE:FBgn0034489
Locus tag
Dmel_CG11209
See related
AllianceGenome:FB:FBgn0034489
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11209; Dmel\CG11209; Ppk6; PPK6
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in neurons and terminal organ. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ppk6 in Genome Data Viewer
Location:
56F11-56F11; 2-90 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20245760..20247624, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16133265..16135129, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene EF-hand domain containing 1.2 Neighboring gene 2-hydroxyacyl-CoA lyase Neighboring gene uncharacterized protein Neighboring gene Arginyltransferase 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
 
enables sodium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
pickpocket 6
Names
CG11209-PA
ppk6-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20245760..20247624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137617.4NP_611461.3  pickpocket 6 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611461.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86LH3
    Conserved Domains (1) summary
    pfam00858
    Location:85476
    ASC; Amiloride-sensitive sodium channel