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Ir56b Ionotropic receptor 56b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37250, updated on 9-Dec-2024

Summary

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Official Symbol
Ir56bprovided by FlyBase
Official Full Name
Ionotropic receptor 56bprovided by FlyBase
Primary source
FLYBASE:FBgn0034456
Locus tag
Dmel_CG15121
See related
AllianceGenome:FB:FBgn0034456
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
56b; CG15121; DmelIR56b; Dmel\CG15121; IR56b
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in labellar taste bristle; leg taste bristle chemosensory neurons; proboscis; and tarsal segment. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Ir56b in Genome Data Viewer
Location:
56D15-56D15; 2-89 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19508167..19509653)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15395672..15397158)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44472 Neighboring gene transfer RNA:Histidine-GTG 1-5 Neighboring gene Ionotropic receptor 56c Neighboring gene Ionotropic receptor 56d

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila. Dweck HKM, et al. Curr Biol, 2022 Apr 25. PMID 35294865, Free PMC Article
  2. Molecular basis of fatty acid taste in Drosophila. Ahn JE, et al. Elife, 2017 Dec 12. PMID 29231818, Free PMC Article
  3. Mechanisms of lactic acid gustatory attraction in Drosophila. Stanley M, et al. Curr Biol, 2021 Aug 23. PMID 34197729
  4. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article
  5. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
ionotropic receptor 56b
Names
CG15121-PB
CG15121-PC
Ir56b-PB
Ir56b-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    19508167..19509653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001414062.1 → NP_001400982.1  ionotropic receptor 56b, isoform B [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZBM7

  2. NM_001414063.1 → NP_001401019.1  ionotropic receptor 56b, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    E3CTQ7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZBM7 A1ZBM7

Gene LinkOut

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