EloC Elongin C [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: EloCprovided by FlyBase
Official Full Name: Elongin Cprovided by FlyBase
Primary source: FLYBASE:FBgn0266711
Locus tag: Dmel_CG9291
See related: AllianceGenome:FB:FBgn0266711
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RH71704; CG9291; dElongin C; Dmel\CG9291; Elongin-C; ElonginC; l(2)SH1299; l(2)SH1520; l(2)SH2 1520
Summary: Enables chromatin binding activity. Involved in imaginal disc-derived wing vein specification; negative regulation of receptor signaling pathway via JAK-STAT; and viral process. Part of Cul2-RING ubiquitin ligase complex and elongin complex. Is expressed in adult head and organism. Orthologous to human ELOC (elongin C). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (19445085..19446286, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (15332590..15333791, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables protein-macromolecule adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in imaginal disc-derived wing vein specification	IGI Inferred from Genetic Interaction more info	PubMed
involved_in negative regulation of receptor signaling pathway via JAK-STAT	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription elongation by RNA polymerase II	IC Inferred by Curator more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info
involved_in viral process	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
part_of Cul2-RING ubiquitin ligase complex	IDA Inferred from Direct Assay more info	PubMed
part_of Cul2-RING ubiquitin ligase complex	IPI Inferred from Physical Interaction more info	PubMed
part_of elongin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of elongin complex	IDA Inferred from Direct Assay more info	PubMed

Names: CG9291-PA; CG9291-PB; EloC-PA; EloC-PB; d-elongin C; elonginC; lethal (2) SH1520

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain