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MFS15 Major Facilitator Superfamily Transporter 15 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37168, updated on 9-Dec-2024

Summary

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Official Symbol
MFS15provided by FlyBase
Official Full Name
Major Facilitator Superfamily Transporter 15provided by FlyBase
Primary source
FLYBASE:FBgn0034392
Locus tag
Dmel_CG15094
See related
AllianceGenome:FB:FBgn0034392
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15094; Dmel\CG15094
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be active in membrane. Is expressed in several structures, including adult head; amnioserosa; embryonic/larval salivary gland; plasmatocyte primordium; and salivary gland body primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See MFS15 in Genome Data Viewer
Location:
55F3-55F3; 2-86 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18794618..18796678, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14682123..14684183, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43964 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Major Facilitator Superfamily Transporter 14 Neighboring gene long non-coding RNA:CR44468

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Embryonic expression patterns of Drosophila ACS family genes related to the human sialin gene. Laridon B, et al. Gene Expr Patterns, 2008 Apr. PMID 18255354
  2. Organ-specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA. Fox RM, et al. Development, 2013 May. PMID 23578928, Free PMC Article
  3. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
  4. Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster. Gao N, et al. Cell Death Differ, 2022 Dec. PMID 35840760, Free PMC Article
  5. Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. Vinci G, et al. PLoS One, 2008 Aug 6. PMID 18682733, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
major facilitator superfamily transporter 15
Names
CG15094-PA
CG15094-PB
MFS15-PA
MFS15-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    18794618..18796678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137531.2 → NP_611375.2  major facilitator superfamily transporter 15, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611375.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZBD9, Q6NR28
    Related
    FBpp0085818
    Conserved Domains (2) summary
    cd06174
    Location:31 → 459
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:18 → 469
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

  2. NM_166308.2 → NP_725828.1  major facilitator superfamily transporter 15, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZBE0, Q6NR28
    Related
    FBpp0085819
    Conserved Domains (2) summary
    cd06174
    Location:13 → 405
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:13 → 368
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZBD9 A1ZBD9
A1ZBE0 A1ZBE0
Q6NR28 Q6NR28

Gene LinkOut

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