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Pepck1 - Phosphoenolpyruvate carboxykinase 1

Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Involved in several processes, including gluconeogenesis; glycerol biosynthetic process; and triglyceride biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including Malpighian tubule primordium; adult head; amnioserosa; anlage in statu nascendi; and epidermis. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to several human genes including PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa