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CG5098 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37063, updated on 9-Dec-2024

Summary

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Official Symbol
CG5098provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034300
Locus tag
Dmel_CG5098
See related
AllianceGenome:FB:FBgn0034300
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5098
Summary
Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in embryonic brain and organism. Human ortholog(s) of this gene implicated in Smith-Magenis syndrome. Orthologous to several human genes including TCF20 (transcription factor 20). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG5098 in Genome Data Viewer
Location:
55B4-55B5; 2-84 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18094940..18101031)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13982445..13988536)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45022 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Trf4-1 involves in mRNA and primary miRNA transcription. Liu Y, et al. Biochem Biophys Res Commun, 2019 Apr 16. PMID 30837153
  2. Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription. Andersen DS, et al. Mol Cell Biol, 2010 Oct. PMID 20679484, Free PMC Article
  3. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Raja SJ, et al. Mol Cell, 2010 Jun 25. PMID 20620954
  4. Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. Lin WH, et al. Dis Model Mech, 2017 Feb 1. PMID 28067623, Free PMC Article
  5. A genome-wide resource for the analysis of protein localisation in Drosophila. Sarov M, et al. Elife, 2016 Feb 20. PMID 26896675, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG5098-PA
CG5098-PB
CG5098-PC
CG5098-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    18094940..18101031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137447.4 → NP_611291.1  uncharacterized protein Dmel_CG5098, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611291.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8DYH9, Q6AWG9
    Related
    FBpp0085911
    Conserved Domains (1) summary
    cl22851
    Location:982 → 1198
    PHD_SF; PHD finger superfamily

  2. NM_001103893.2 → NP_001097363.1  uncharacterized protein Dmel_CG5098, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097363.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q6AWG9
    Conserved Domains (1) summary
    cl22851
    Location:1072 → 1288
    PHD_SF; PHD finger superfamily

  3. NM_001274137.1 → NP_001261066.1  uncharacterized protein Dmel_CG5098, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261066.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KFU8
    Conserved Domains (1) summary
    cl22851
    Location:1068 → 1284
    PHD_SF; PHD finger superfamily

  4. NM_001316427.1 → NP_001303356.1  uncharacterized protein Dmel_CG5098, isoform D [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A126GUN5
    Conserved Domains (1) summary
    cl22851
    Location:1068 → 1284
    PHD_SF; PHD finger superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KFU8 A0A0B4KFU8
A0A126GUN5 A0A126GUN5
Q6AWG9.1 Q6AWG9

Gene LinkOut

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