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Mapmodulin mapmodulin [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37043, updated on 9-Dec-2024

Summary

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Official Symbol
Mapmodulinprovided by FlyBase
Official Full Name
mapmodulinprovided by FlyBase
Primary source
FLYBASE:FBgn0034282
Locus tag
Dmel_CG5784
See related
AllianceGenome:FB:FBgn0034282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:fe3A2; CG5784; CT18148; CT42180; Dmel\CG5784
Summary
Predicted to enable histone binding activity. Predicted to be involved in nucleocytoplasmic transport. Located in nucleoplasm. Is expressed in several structures, including adult brain cell body rind; central brain primordium; ganglia; gonad; and ventral nerve cord primordium. Used to study candidiasis. Orthologous to several human genes including ANP32A (acidic nuclear phosphoprotein 32 family member A); ANP32B (acidic nuclear phosphoprotein 32 family member B); and ANP32CP (acidic nuclear phosphoprotein 32 family member C, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Mapmodulin in Genome Data Viewer
Location:
54F4-54F4; 2-84 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17866178..17872015, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13753683..13759520, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene orai Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44417 Neighboring gene three rows Neighboring gene uncharacterized protein Neighboring gene Eag-like K[+] channel Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An inducible nuclear body in the Drosophila germinal vesicle. Singer AB, et al. Nucleus, 2011 Sep-Oct. PMID 21941118, Free PMC Article
  2. Messenger RNA is a functional component of a chromatin insulator complex. Matzat LH, et al. EMBO Rep, 2013 Oct. PMID 23917615, Free PMC Article
  3. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
  4. Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1. Lou WP, et al. Front Mol Neurosci, 2017. PMID 29379413, Free PMC Article
  5. Direct Testing for Allele-Specific Expression Differences Between Conditions. León-Novelo L, et al. G3 (Bethesda), 2018 Feb 2. PMID 29167272, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in nucleocytoplasmic transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleoplasm HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mapmodulin
Names
CG5784-PA
CG5784-PB
CG5784-PC
CG5784-PD
Mapmodulin-PA
Mapmodulin-PB
Mapmodulin-PC
Mapmodulin-PD
anon-fast-evolving-3A2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17866178..17872015 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079056.4 → NP_523780.1  mapmodulin, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523780.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2VEM0, Q0E936, Q9V895
    UniProtKB/TrEMBL
    B7YZR7
    Related
    FBpp0086001
    Conserved Domains (3) summary
    sd00033
    Location:17 → 39
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:60 → 103
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:40 → 95
    LRR_8; Leucine rich repeat

  2. NM_166258.3 → NP_725732.1  mapmodulin, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725732.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A2VEM0, Q0E936, Q9V895
    UniProtKB/TrEMBL
    B7YZR7
    Related
    FBpp0086002
    Conserved Domains (3) summary
    sd00033
    Location:17 → 39
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:60 → 103
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:40 → 95
    LRR_8; Leucine rich repeat

  3. NM_001169713.2 → NP_001163184.1  mapmodulin, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163184.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JGK5
    Conserved Domains (3) summary
    sd00033
    Location:17 → 39
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:60 → 103
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:40 → 95
    LRR_8; Leucine rich repeat

  4. NM_001103891.3 → NP_001097361.1  mapmodulin, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097361.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JGK5
    Conserved Domains (3) summary
    sd00033
    Location:17 → 39
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:60 → 103
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:40 → 95
    LRR_8; Leucine rich repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7YZR7 B7YZR7
E1JGK5 E1JGK5
Q9V895.1 Q9V895

Gene LinkOut

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