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OstDelta Oligosaccharide transferase Delta subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37029, updated on 9-Dec-2024

Summary

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Official Symbol
OstDeltaprovided by FlyBase
Official Full Name
Oligosaccharide transferase Delta subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0034277
Locus tag
Dmel_CG6370
See related
AllianceGenome:FB:FBgn0034277
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6370; Dmel\CG6370; OST
Summary
Involved in encapsulation of foreign target. Located in endomembrane system. Is expressed in adult head; adult heart; and organism. Orthologous to human RPN2 (ribophorin II). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See OstDelta in Genome Data Viewer
Location:
54E8-54E8; 2-84 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17764574..17767070, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13652079..13654575, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene HLH54F Neighboring gene acyl-CoA oxidase 1 Neighboring gene antisense RNA:CR44416 Neighboring gene mir-3643 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Altered protein glycosylation predicts Alzheimer's disease and modulates its pathology in disease model Drosophila. Frenkel-Pinter M, et al. Neurobiol Aging, 2017 Aug. PMID 28552182
  2. Endoplasmic reticulum proteins Meigo and Gp93 govern dendrite targeting by regulating Toll-6 localization. Kamemura K, et al. Dev Biol, 2022 Apr. PMID 35134382
  3. Insights from Drosophila melanogaster model of Alzheimer's disease. Tue NT, et al. Front Biosci (Landmark Ed), 2020 Jan 1. PMID 31585881
  4. Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. Mortimer NT, et al. PLoS Pathog, 2012. PMID 22829770, Free PMC Article
  5. The life history of Drosophila sperm involves molecular continuity between male and female reproductive tracts. McCullough EL, et al. Proc Natl Acad Sci U S A, 2022 Mar 15. PMID 35254899, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in encapsulation of foreign target IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of oligosaccharyltransferase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
oligosaccharide transferase delta subunit
Names
CG6370-PA
CG6370-PB
OstDelta-PA
OstDelta-PB
oligosaccharide transferase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17764574..17767070 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299620.1 → NP_001286549.1  oligosaccharide transferase delta subunit, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286549.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LFR4
    Conserved Domains (1) summary
    pfam05817
    Location:8 → 622
    Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II

  2. NM_137421.3 → NP_611265.1  oligosaccharide transferase delta subunit, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611265.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K110
    Related
    FBpp0088527
    Conserved Domains (1) summary
    pfam05817
    Location:8 → 623
    Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LFR4 A0A0B4LFR4
Q7K110 Q7K110

Gene LinkOut

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