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CG6424 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37012, updated on 9-Dec-2024

Summary

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Official Symbol
CG6424provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0028494
Locus tag
Dmel_CG6424
See related
AllianceGenome:FB:FBgn0028494
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.96; anon-WO0153538.32; anon-WO0153538.33; anon-WO0153538.34; BcDNA:GH05095; Dmel\CG6424; GH05095
Summary
Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to several human genes including FAM13B (family with sequence similarity 13 member B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG6424 in Genome Data Viewer
Location:
54E1-54E1; 2-84 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17703335..17719346, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13590840..13606851, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U snoRNA host gene 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dachs ligand with SH3s Neighboring gene Sorting nexin 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila. DeSalvo MK, et al. Glia, 2011 Sep. PMID 21351158, Free PMC Article
  2. Proper splicing contributes to visual function in the aging Drosophila eye. Stegeman R, et al. Aging Cell, 2018 Oct. PMID 30003673, Free PMC Article
  3. Using the P[wHy] hybrid transposable element to disrupt genes in region 54D-55B in Drosophila melanogaster. Mohr SE, et al. Genetics, 2002 Sep. PMID 12242231, Free PMC Article
  4. Extensive identification and analysis of conserved small ORFs in animals. Mackowiak SD, et al. Genome Biol, 2015 Sep 14. PMID 26364619, Free PMC Article
  5. Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes. Takahashi H, et al. Sci Rep, 2020 Oct 1. PMID 33004976, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6424-PA
CG6424-PB
CG6424-PC
CG6424-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17703335..17719346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166246.3 → NP_725709.1  uncharacterized protein Dmel_CG6424, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725709.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E938, T2GGE1
    Related
    FBpp0086046
    Conserved Domains (1) summary
    PRK02224
    Location:462 → 626
    PRK02224; chromosome segregation protein; Provisional

  2. NM_001299617.1 → NP_001286546.1  uncharacterized protein Dmel_CG6424, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286546.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E938, T2GGE1
    Conserved Domains (1) summary
    PRK02224
    Location:462 → 626
    PRK02224; chromosome segregation protein; Provisional

  3. NM_137405.4 → NP_611249.2  uncharacterized protein Dmel_CG6424, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611249.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E938, T2GGE1
    Related
    FBpp0086047
    Conserved Domains (1) summary
    PRK02224
    Location:462 → 626
    PRK02224; chromosome segregation protein; Provisional

  4. NM_001169710.2 → NP_001163181.1  uncharacterized protein Dmel_CG6424, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163181.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E938, T2GGE1
    Conserved Domains (1) summary
    PRK02224
    Location:462 → 626
    PRK02224; chromosome segregation protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0E938 Q0E938
Q9U4H1 Q9U4H1

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