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CG14483 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36995, updated on 4-Jan-2025

Summary

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Official Symbol
CG14483provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034248
Locus tag
Dmel_CG14483
See related
AllianceGenome:FB:FBgn0034248
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14483
Summary
Predicted to enable unfolded protein binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in embryonic/larval midgut and organism. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 12. Orthologous to human PET100 (PET100 cytochrome c oxidase chaperone). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG14483 in Genome Data Viewer
Location:
54C10-54C11; 2-83 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17585195..17586294, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13472700..13473799, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45274 Neighboring gene antisense RNA:CR45275 Neighboring gene Rho GTPase activating protein at 54D Neighboring gene icln Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antagonistic pleiotropy for life-history traits at the gene expression level. Bochdanovits Z, et al. Proc Biol Sci, 2004 Feb 7. PMID 15101424, Free PMC Article
  2. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Raja SJ, et al. Mol Cell, 2010 Jun 25. PMID 20620954
  3. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article
  4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
  5. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial cytochrome c oxidase assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14483-PA
CG14483-PB
CG14483-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17585195..17586294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299612.1 → NP_001286541.1  uncharacterized protein Dmel_CG14483, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286541.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QPR8
    Conserved Domains (1) summary
    pfam09803
    Location:1 → 63
    Pet100

  2. NM_001274130.2 → NP_001261059.1  uncharacterized protein Dmel_CG14483, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001261059.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QPR8
    Conserved Domains (1) summary
    pfam09803
    Location:1 → 63
    Pet100

  3. NM_137391.4 → NP_611235.1  uncharacterized protein Dmel_CG14483, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611235.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QPR8
    Related
    FBpp0086059
    Conserved Domains (1) summary
    pfam09803
    Location:1 → 63
    Pet100
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4QPR8 Q4QPR8

Gene LinkOut

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