U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tes Testin [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36965, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Tesprovided by FlyBase
Official Full Name
Testinprovided by FlyBase
Primary source
FLYBASE:FBgn0034223
Locus tag
Dmel_CG6522
See related
AllianceGenome:FB:FBgn0034223
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6522; Dmel\CG6522; dTES
Summary
Predicted to enable zinc ion binding activity. Located in actin cytoskeleton and cytoplasm. Is expressed in larval central nervous system. Orthologous to human LMCD1 (LIM and cysteine rich domains 1) and TES (testin LIM domain protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Tes in Genome Data Viewer
Location:
54B16-54B16; 2-82 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17465879..17469177, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13353384..13356682, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene roadblock Neighboring gene uncharacterized protein Neighboring gene quaking related 54B Neighboring gene insensible

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Generation of stable Drosophila cell lines using multicistronic vectors. González M, et al. Sci Rep, 2011. PMID 22355594, Free PMC Article
  2. Slam protein dictates subcellular localization and translation of its own mRNA. Yan S, et al. PLoS Biol, 2017 Dec. PMID 29206227, Free PMC Article
  3. Insensible is a novel nuclear inhibitor of Notch activity in Drosophila. Coumailleau F, et al. PLoS One, 2014. PMID 24902027, Free PMC Article
  4. Retracing the path of planar cell polarity. Schenkelaars Q, et al. BMC Evol Biol, 2016 Apr 2. PMID 27039172, Free PMC Article
  5. Molecular organization of Drosophila neuroendocrine cells by Dimmed. Park D, et al. Curr Biol, 2011 Sep 27. PMID 21885285, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in actin cytoskeleton IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
testin
Names
CG6522-PA
Tes-PA
testin ortholog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17465879..17469177 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137371.4 → NP_611215.1  testin [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611215.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAT5, H1UUM7
    Related
    FBpp0086110
    Conserved Domains (4) summary
    cd09340
    Location:627 → 684
    LIM1_Testin_like; The first LIM domain of Testin-like family
    cd09341
    Location:691 → 748
    LIM2_Testin_like; The second LIM domain of Testin-like family
    cd09829
    Location:110 → 197
    PET_testin; The PET domain of Testin
    cl02475
    Location:755 → 810
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZAT5 A1ZAT5
Q8T0B0 Q8T0B0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous