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caly - calypso

Enables chromatin binding activity and cysteine-type deubiquitinase activity. Involved in heterochromatin formation and specification of segmental identity, abdomen. Located in chromatin and nucleus. Part of PR-DUB complex. Is expressed in embryonic brain; larval ventral nerve cord; and organism. Human ortholog(s) of this gene implicated in basal cell carcinoma; extrahepatic bile duct adenocarcinoma; and uveal melanoma. Orthologous to human BAP1 (BRCA1 associated deubiquitinase 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa