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Armcx3 armadillo repeat containing, X-linked 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 367902, updated on 27-Nov-2024

Summary

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Official Symbol
Armcx3provided by RGD
Official Full Name
armadillo repeat containing, X-linked 3provided by RGD
Primary source
RGD:1549739
See related
EnsemblRapid:ENSRNOG00000025730 AllianceGenome:RGD:1549739
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to act upstream of or within several processes, including axonal transport of mitochondrion; mitochondrion organization; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; mitochondrial outer membrane; and nucleus. Predicted to be active in mitochondrion. Orthologous to human ARMCX3 (armadillo repeat containing X-linked 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 383.1), Heart (RPKM 305.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Armcx3 in Genome Data Viewer
Location:
Xq32
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (102230464..102234017)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (97937115..97942098)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (105573909..105577480)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene protein ARMCX6-like Neighboring gene armadillo repeat containing, X-linked 6 Neighboring gene armadillo repeat containing, X-linked 2 Neighboring gene cofilin 1, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10. Mou Z, et al. J Biol Chem, 2009 May 15. PMID 19304657, Free PMC Article
  2. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. López-Doménech G, et al. Nat Commun, 2012 May 8. PMID 22569362
  3. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sox10 is a membrane-associated factor whose transcriptional function is increased by direct interactions with ARMCX3
    Title: The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within axonal transport of mitochondrion ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within mitochondrion organization ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within protein localization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
armadillo repeat-containing X-linked protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014273.1 → NP_001014295.1  armadillo repeat-containing X-linked protein 3

    See identical proteins and their annotated locations for NP_001014295.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083747
    UniProtKB/Swiss-Prot
    Q5XID7
    UniProtKB/TrEMBL
    A0A8I6AF34
    Related
    ENSRNOP00000033859.4, ENSRNOT00000029664.7
    Conserved Domains (2) summary
    sd00043
    Location:156 → 190
    ARM; armadillo repeat [structural motif]
    pfam04826
    Location:112 → 363
    Arm_2; Armadillo-like

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    102230464..102234017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XID7.1 GenPept UniProtKB/Swiss-Prot:Q5XID7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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