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Cdk5 - Cyclin-dependent kinase 5

Enables cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including determination of adult lifespan; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and melanotic encapsulation of foreign target. Part of protein kinase 5 complex. Is expressed in adult head; organism; presumptive embryonic/larval central nervous system; and presumptive embryonic/larval nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly 7 with cerebellar hypoplasia. Orthologous to human CDK5 (cyclin dependent kinase 5). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Cdk5

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Species Gene Architecture aa