scb - scab

Enables protein heterodimerization activity. Involved in several processes, including behavioral response to ethanol; dorsal trunk growth, open tracheal system; and heart development. Located in apical plasma membrane; basal plasma membrane; and cytoplasm. Part of integrin complex. Is expressed in several structures, including Kenyon cell; epithelium; follicle cell; synaptic neuropil domain; and synaptic neuropil subdomain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); retinal vascular disease (multiple); and von Willebrand's disease (multiple). Orthologous to several human genes including ITGA9 (integrin subunit alpha 9). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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