Colec11 collectin sub-family member 11 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Colec11provided by RGD
Official Full Name: collectin sub-family member 11provided by RGD
Primary source: RGD:1309678
See related: EnsemblRapid:ENSRNOG00000008373 AllianceGenome:RGD:1309678
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable several functions, including calcium-dependent carbohydrate binding activity; identical protein binding activity; and monosaccharide binding activity. Predicted to be involved in defense response to symbiont; positive regulation of opsonization; and proteolysis. Predicted to be located in centrosome and ribosome. Predicted to be part of collagen trimer and ribonucleoprotein complex. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in 3MC syndrome 2. Orthologous to human COLEC11 (collectin subfamily member 11). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 272.7) and Heart (RPKM 22.4) See more
Orthologs: human mouse all
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Genomic context

Location:: 6q16

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (50952357..50984845, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (45223974..45256640, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (47857767..47889961, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AU047740 (e-PCR)
- UniSTS:110210

RH133753 (e-PCR)
- UniSTS:217036

RH137776 (e-PCR)
- UniSTS:219863

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables D-mannose binding	ISO Inferred from Sequence Orthology more info
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables calcium ion binding	ISO Inferred from Sequence Orthology more info
enables calcium-dependent carbohydrate binding	ISO Inferred from Sequence Orthology more info
enables fucose binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables oligosaccharide binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in antimicrobial humoral response	ISO Inferred from Sequence Orthology more info
involved_in complement activation	ISO Inferred from Sequence Orthology more info
involved_in complement activation, lectin pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of opsonization	ISO Inferred from Sequence Orthology more info
involved_in proteolysis	ISO Inferred from Sequence Orthology more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of collagen trimer	IEA Inferred from Electronic Annotation more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: collectin-11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.