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Pgm2b Phosphoglucomutase 2b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36649, updated on 9-Dec-2024

Summary

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Official Symbol
Pgm2bprovided by FlyBase
Official Full Name
Phosphoglucomutase 2bprovided by FlyBase
Primary source
FLYBASE:FBgn0033969
Locus tag
Dmel_CG10202
See related
AllianceGenome:FB:FBgn0033969
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.148; CG10202; Dmel\CG10202
Summary
Predicted to enable phosphopentomutase activity. Predicted to be involved in purine ribonucleoside salvage. Is expressed in spermatozoon. Orthologous to human PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2 like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Pgm2b in Genome Data Viewer
Location:
51C4-51C4; 2-72 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14817857..14819987, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10705362..10707492, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene knot Neighboring gene hase und igel Neighboring gene long non-coding RNA:CR45329 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Direct regulation of knot gene expression by Ultrabithorax and the evolution of cis-regulatory elements in Drosophila. Hersh BM, et al. Development, 2005 Apr. PMID 15753212
  2. Toxicological Study and Genetic Basis of BTEX Susceptibility in Drosophila melanogaster. Adebambo TH, et al. Front Genet, 2020. PMID 33193742, Free PMC Article
  3. Epi-MEIF: detecting higher order epistatic interactions for complex traits using mixed effect conditional inference forests. Saha S, et al. Nucleic Acids Res, 2022 Oct 28. PMID 36107776, Free PMC Article
  4. Identification of proteasome components required for apical localization of Chaoptin using functional genomics. Yano H, et al. J Neurogenet, 2012 Mar. PMID 22417167
  5. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables intramolecular phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphopentomutase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in purine ribonucleoside salvage IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
phosphoglucomutase 2b
Names
CG10202-PA
Pgm2b-PA
NP_610992.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    14817857..14819987 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137148.3 → NP_610992.2  phosphoglucomutase 2b [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610992.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z9V3, H8F4Q3
    Related
    FBpp0086594
    Conserved Domains (2) summary
    cd05799
    Location:67 → 607
    PGM2; This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and ...
    PTZ00150
    Location:26 → 621
    PTZ00150; phosphoglucomutase-2-like protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z9V3 A1Z9V3
Q961H8 Q961H8

Gene LinkOut

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